To stay your dog’s uncontrollable scratching, relieve hotspots or help his dry skin you need more than just CBD – you should also leverage bromelain’s and quercetin’s powerful antihistamine properties.
Bromelain and Quercetin have been called “Nature’s Benadryl” due to their powerful anti-histamine properties. Benadryl is a well-known over the counter antihistamine and has been used to treat everything from sinusitis to skin allergies. Antihistamines relieve allergies by reducing the action of inflammatory messenger molecules (called histamines) from the cells of the immune system. Anti-histamines may reduce the release of histamines or block the cell receptors that bind histamine to cause the swelling, redness, and itching common to allergic reactions in dogs.
Bromelain – from pineapple, it digests histamine
Natural antihistamines like bromelain and quercetin do this heavy lifting, without the side effects of over-the-counter medicines like Benadryl – like drowsiness, dizziness, and in severe cases vomiting, seizures, and even death. The University of Maryland Medical Center describes bromelain as a mixture of enzymes found in the stem and juice of pineapples that digest proteins, and has been approved by the German Commission for the treatment of inflammation. Other studies have shown that bromelain reduces the mucus production and cough associated with sinusitis and the swelling and inflammation of the respiratory tract associated with hay fever. The enzymes in bromelain may also digest histamine, reducing histamine levels caused by the allergic response.
Quercetin – an antioxidant flavonoid
Quercetin is a flavonoid found in fruits and vegetables such as grapes and onions, and is known for its antioxidant activities. Quercetin has been shown to reduce oxidative stress of the cells in the sinus cavities. Studies have also shown that quercetin stabilizes the mast cells of the immune system. These mast cells, when activated, release inflammatory messenger molecules such as histamine which leads to inflammation and the allergic response. By stabilizing the mast cells, quercetin may lower the levels of histamine due to exposure to allergens.
Working together to normalize the inflammatory system
Bromelain and quercetin both individually modulate portions of the inflammatory system to support normal immune function in the presence of allergens. Interestingly, when combined the effects of Bromelain and quercetin synergize for even better results. The exact mechanism of this synergy is not fully understood. However some scientists suggest that in addition to its own effects bromelain may increase the absorption of quercetin in the digestive tract.
Watching your dog lick his paws and gnaw and scratch at itches that persist due to allergies isn’t just uncomfortable to him, it’s stressful for you. Rather than turn to pharmaceuticals when your dog’s immune system malfunctions, support your dog’s healthy immune system function with bromelain and quercetin – which are still more effective when working with CBD to improve skin health. And when they feel better, you’ll feel better!